Mechanochemical Prebiotic Peptide Bond Formation**

The presence of amino acids on the prebiotic Earth, either stemming from endogenous chemical routes or delivered by meteorites, is consensually accepted. Prebiotically plausible pathways to peptides inactivated are still unclear as most oligomerization approaches rely thermodynamically disfavored reactions in solution. Now, a combination prebiotically minerals and mechanochemical activation enables glycine at ambient temperature absence water. Raising reaction increases degree concomitantly with formation commonly unwanted cyclic dimer (DKP). However, DKP productive intermediate glycine. findings this research show that peptide bond dynamic process provides alternative towards oligopeptides establishes new synthetic for chemistry.